Assessing the Biological Significance of Gene Expression Signatures and Co-Expression Modules by Studying Their Network Properties
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منابع مشابه
Assessing the Biological Significance of Gene Expression Signatures and Co-Expression Modules by Studying Their Network Properties
Microarray experiments have been extensively used to define signatures, which are sets of genes that can be considered markers of experimental conditions (typically diseases). Paradoxically, in spite of the apparent functional role that might be attributed to such gene sets, signatures do not seem to be reproducible across experiments. Given the close relationship between function and protein i...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0017474